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[Using transient transfection experiments with the GAPDH promoter region linked to a luciferase reporter gene, we found that GAPDH was transcriptionally activated by hypoxia in each of three human prostate cancer cell lines tested, with the greatest level of induction in the most differentiated cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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