. . . . . . . "[Training reduced 4-HNE (-10%; P?0.04), PC (-21%; P?0.05), 8-isoprostane (-26%; P?0.02) and leptin levels (-33%; P?0.01); had a tendency to decrease IL-6 levels (-21%; P=0.07) and IR (-17%; P=0.10); and increased manganese SOD (MnSOD) levels (+47%; P?0.01).Conclusion:Endurance exercise reduced skeletal muscle-specific and systemic oxidative damage while improving IR and cytokine profile associated with obesity, independent of weight loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-01-25"^^ . . "Gene-disease associations manually curated."@en . "DisGeNET evidence - CURATED"@en . "2017-10-17T13:14:16+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .