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[Chronic treatments with two ?-secretase modulators, ibuprofen and CHF5074, disclosed higher activity of CHF5074 in ameliorating brain plaque deposition and spatial memory deficits in transgenic mice expressing human amyloid precursor protein (hAPP) with Swedish and London mutations (APP(SL) mice).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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