. . . . . . . "[Importantly, we found that Trien blocked the receptor for AGEs (RAGE), downregulated ?-site APP cleaving enzyme 1 (BACE1), inhibited amyloidogenic APP cleavage, and subsequently reduced A? levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-01-25"^^ . . "Gene-disease associations manually curated."@en . "DisGeNET evidence - CURATED"@en . "2017-10-17T13:10:37+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .