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[Because a major feature of Cter-NPM1 mutants responsible for AML is a reduction in stability of the protein and thus prevalence of a denatured state even under physiological conditions, our findings may pave the way to further studies with the aim of designing chemicals capable of interacting with the 'pathological' mutants to stabilize the native conformation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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